Recurrent Miscarriage related to coagulation factor XIII
نویسندگان
چکیده
منابع مشابه
Coagulation Factor XII Congenital Deficiency in Women with Recurrent Miscarriage
Factor XII (Hageman factor) is an important protease that plays a major role in the initiation of the intrinsic pathway of blood coagulation and fibrinolysis and kinin formation. It is still unclear whether factor XII deficiency causes any disorders during pregnancy. Because the main clinical feature in patients with factor XII deficiency is thrombosis rather than bleeding, low dose aspirin wou...
متن کاملAdvances of Coagulation Factor XIII
OBJECTIVE To provide a comprehensive literature review on roles of coagulation factor XIII (FXIII) in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy. DATA SOURCES All articles in PubMed with key words "Coagulation factor XIII", "wound", "leukemia", "tumor", "bone," and "pregnancy" with published date from 2001 to 2016 were included in the study. Frequently cited publicat...
متن کاملInhibition of Fibrinolysis by Coagulation Factor XIII
The inhibitory effect of coagulation factor XIII (FXIII) on fibrinolysis has been studied for at least 50 years. Our insight into the underlying mechanisms has improved considerably, aided in particular by the discovery that activated FXIII cross-links α2-antiplasmin (α2AP) to fibrin. In this review, the most important effects of different cross-linking reactions on fibrinolysis are summarized....
متن کاملImmunological studies of coagulation factor XIII.
Human fibrin-stabilizing factor (Factor XIII) has been studied immunologically by the preparation of specific anti-Factor XIII antiserum in rabbits. On immunodiffusion it was found that normal plasma produced two precipitin lines. One of the precipitin lines was identical with that present in soluble platelet extract (the alpha-component), the other with that present in normal serum (beta-compo...
متن کاملRecurrent miscarriage
Recurrent miscarriages are one or more pregnancy losses before 20-24 weeks of gestation or below a fetal weight of 500 g (Pic. 1). About 1% of women in reproductive age are affected by recurrent miscarriages. The majority of patients are counseled to try to conceive again, and chances are about 60% that the next pregnancy is successful without treatment. However, each additional loss worsens th...
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ژورنال
عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis
سال: 2009
ISSN: 1880-8808,0915-7441
DOI: 10.2491/jjsth.20.519